Result for the search of Gene Name/NCBI ID(s): 'TPM3'

Total of fusion sequences: 27 (from 1493742 parsed EST/mRNAs. Last update 2019-12-05 16:32:10)

Organism	Fusion: Graphical View, Annotation, PPI network	Head Gene (1)			Tail Gene (2)			Rank, Deviation: Eloc(x) Sloc(y)	Fusion type RNA	Hi-C, RNAseq, Mass-spec evidences	Cancer Breakpoint, PubMed(s)
		Name(s)1, transcript	Start1..End1 Ident1%	Strand1 Chrom1	Name(s)2, transcript	Start2..End2 Ident2%	Strand2 Chrom2
1	2	3	4,5,6	7,19	8	9,10,11	12,25	13,14,15	32	16	17
1 Homo Sapiens	SplGraphs M55336 ANNOTATION OF CHIMERA FUSION GenBank ID: M55336 FASTA UniProtKB: Q00182 Oncogene tyrosine protein kinase receptor (Fragment) Fusion Gene(s): trk2 Head Gene (1) Alignment: TPM3 | OMIM: 191030 Tail Gene (2) Alignment: NTRK1 | OMIM: 191315 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 7170 1 - 154183108 154183187 9 1 oncogene 4914 1 + 156875547 156876180 6 1 oncogene 354 hg38 Domains of the full fusion Envelope E-value Score Description name (Pfam, InterPro, SMART) length from to Pkinase_Tyr (PF07714, IPR001245) 260 74 345 5.9e-98 313.300 Protein tyrosine kinase Updated: 2019-02-21 Owner: ChiTaRS	TPM3 A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4G8 A0A0S2Z4I4 A0A2R2Y2Q3 A0A494C034 A0A494C0G0 A0A494C0P6 D6R904 D6RGJ6 J3KN67 P06753 Q5HYB6 Q5VU61 Q5VU62 Q8NAH0 Q8NI98 NM_001278189.1	59..138 100.0%	- 1	NTRK1 E9PQG0 J3KP20 P04629 X5D991 X5DR71 NM_001007792.1	129..354 99.6%	+ 1	1 0 0	exon-exon	1RNA-seq	BREAKPOINTs more info 1384673 1695324 2869410 7590742 22895193 24705251 25204415 25500544 26001971 26863915 26892443 27259011 28097808 28877062 30276917
2 Homo Sapiens	SplGraphs BF790588 ANNOTATION OF CHIMERA FUSION GenBank ID: BF790588 FASTA Head Gene (1) Alignment: MTERF4 | OMIM: 615393 Tail Gene (2) Alignment: TPM3 | OMIM: 191030 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 130916 2 - 241096100 241096310 4 1 protein-coding 7170 1 - 154172908 154191305 5 1 oncogene 743 hg38 Domains of the full fusion Envelope E-value Score Description name (Pfam, InterPro, SMART) length from to DUF1110 (PF06533, IPR010535) 188 56 116 0.0084 2.200 Protein of unknown function (DUF1110) mTERF (PF02536, IPR003690, SM00733) 313 56 278 2.4e-21 62.100 mTERF Tropomyosin (PF00261, IPR000533) 237 353 443 7.8e-32 96.600 Tropomyosin Updated: 2019-02-02 Owner: ChiTaRS	MTERF4 B4DFP7 B4DKD5 B5MBW3 C9JNJ7 C9JX74 E7EW93 H7C1N9 H7C316 H7C3Q3 L8E9B8 Q7Z6M4 XM_017003382.2	2..209 100.0%	- 2	TPM3 A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4G8 A0A0S2Z4I4 A0A2R2Y2Q3 A0A494C034 A0A494C0G0 A0A494C0P6 D6R904 D6RGJ6 J3KN67 P06753 Q5HYB6 Q5VU61 Q5VU62 Q8NAH0 Q8NI98 NM_152263.3	204..644 100.0%	- 1	1 0 0	exon-exon	Spes-1
3 Homo Sapiens	ChimerDB M55337 ANNOTATION OF CHIMERA FUSION GenBank ID: M55337 FASTA UniProtKB: Q04227 Oncogene tyrosine protein kinase receptor (Fragment) Fusion Gene(s): trk4 Head Gene (1) Alignment: TPM3 | OMIM: 191030 Tail Gene (2) Alignment: NTRK1 | OMIM: 191315 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 7170 1 - 154183108 154183187 9 1 oncogene 4914 1 + 156875547 156876153 6 1 oncogene 354 hg38 Domains of the full fusion Envelope E-value Score Description name (Pfam, InterPro, SMART) length from to Pkinase_Tyr (PF07714, IPR001245) 260 74 345 5.9e-98 313.300 Protein tyrosine kinase Updated: 2019-02-21 Owner: ChiTaRS	TPM3 A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4G8 A0A0S2Z4I4 A0A2R2Y2Q3 A0A494C034 A0A494C0G0 A0A494C0P6 D6R904 D6RGJ6 J3KN67 P06753 Q5HYB6 Q5VU61 Q5VU62 Q8NAH0 Q8NI98 NM_001278189.1	86..165 100.0%	- 1	NTRK1 E9PQG0 J3KP20 P04629 X5D991 X5DR71 NM_001007792.1	156..354 99.5%	+ 1	1 0 0	exon-exon	1RNA-seq	BREAKPOINTs more info 1384673 1695324 2869410 7590742 22895193 24705251 25204415 25500544 26001971 26863915 26892443 27259011 28097808 28877062 30276917
4 Homo Sapiens	SplGraphs AW853022 ANNOTATION OF CHIMERA FUSION GenBank ID: AW853022 FASTA Head Gene (1) Alignment: TPM3 | OMIM: 191030 Tail Gene (2) Alignment: SEC24D | OMIM: 607186 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 7170 1 - 154186095 154186492 9 0 oncogene 9871 4 - 118722843 118723080 23 1 protein-coding 636 hg38 Updated: 2019-02-20 Owner: ChiTaRS	TPM3 A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4G8 A0A0S2Z4I4 A0A2R2Y2Q3 A0A494C034 A0A494C0G0 A0A494C0P6 D6R904 D6RGJ6 J3KN67 P06753 Q5HYB6 Q5VU61 Q5VU62 Q8NAH0 Q8NI98 NM_001278189.1	9..404 99.5%	- 1	SEC24D D6RAE2 D6RBM1 D6RGJ5 E9PC44 E9PDM8 E9PG84 O94855 Q49AI3 Q4W5D3 XM_024454293.1	395..632 98.8%	- 4	1 0 0	intron-exon
5 Homo Sapiens	AB795239 ANNOTATION OF CHIMERA FUSION GenBank ID: AB795239 FASTA UniProtKB: M1VPF4 Tyrosine-protein kinase receptor (EC 2.7.10.1) Fusion Gene(s): TPM3-ROS1 Head Gene (1) Alignment: TPM3 | OMIM: 191030 Tail Gene (2) Alignment: ROS1 | OMIM: 165020 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 7170 1 - 154170400 154192043 10 1 oncogene 6098 6 - 117288478 117321396 44 1 oncogene 2217 hg38 Domains of the full fusion Envelope E-value Score Description name (Pfam, InterPro, SMART) length from to Tropomyosin_1 (PF12718, IPR000533) 143 15 161 4.5e-38 116.800 Tropomyosin like Tropomyosin (PF00261, IPR000533) 237 56 297 5.9e-85 270.500 Tropomyosin Pkinase_Tyr (PF07714, IPR001245) 260 330 600 1.1e-100 322.400 Protein tyrosine kinase Updated: 2019-01-29 Owner: ChiTaRS	TPM3 A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4G8 A0A0S2Z4I4 A0A2R2Y2Q3 A0A494C034 A0A494C0G0 A0A494C0P6 D6R904 D6RGJ6 J3KN67 P06753 Q5HYB6 Q5VU61 Q5VU62 Q8NAH0 Q8NI98 NM_152263.3	1..800 100.0%	- 1	ROS1 H0Y3T9 P08922 Q5H8Y1 XM_011536053.2	799..2217 100.0%	- 6	1 0 0	exon-exon		BREAKPOINTs more info 22327623 22327623 24445538 25742289
6 Homo Sapiens	AF112866 ANNOTATION OF CHIMERA FUSION GenBank ID: AF112866 FASTA Head Gene (1) Alignment: TPM3 | OMIM: 191030 Tail Gene (2) Alignment: ALK | OMIM: 105590 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 7170 1 - 154163102 154165390 1 1 oncogene 238 2 - 29223530 29907015 2 1 oncogene 3394 hg38 Updated: 2019-02-20 Owner: ChiTaRS	TPM3 A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4G8 A0A0S2Z4I4 A0A2R2Y2Q3 A0A494C034 A0A494C0G0 A0A494C0P6 D6R904 D6RGJ6 J3KN67 P06753 Q5HYB6 Q5VU61 Q5VU62 Q8NAH0 Q8NI98 NM_152263.3	1..2289 99.6%	- 1	ALK A0A024A2P5 A0A087WZL3 A0A097F6U9 A0A0K2YUJ3 B2MXD7 B2MXD8 B2MXD9 B2MXE0 B2MXE1 B2MXE2 B2MXE3 B2MXE4 B2MXE5 B2MXE6 B2MXE7 B6D4Y1 B6D4Y2 B6D4Y3 B6D4Y5 B6D4Y6 B6D4Y7 B6D4Y8 D1MAM0 D1MAM1 D1MAM2 D1MAM3 D1MAM4 D1MAM5 E7EPW7 F0UY65 F0UY66 H7BZ33 Q580I3 Q9UM73 XM_024452779.1	1692..3394 95.1%	- 2	0 65535 7298	exon-exon		BREAKPOINTs more info 10216106 10610119 10934142 12707379 24445538 24875859 26647767 26773439 26892443 29329131 29405994
7 Homo Sapiens	AF362886 ANNOTATION OF CHIMERA FUSION GenBank ID: AF362886 FASTA Head Gene (1) Alignment: TPM3 | OMIM: 191030 Tail Gene (2) Alignment: ALK | OMIM: 105590 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 7170 1 - 154170400 154172104 5 1 oncogene 238 2 - 29223441 29223536 20 1 oncogene 308 hg38 Domains of the full fusion Envelope E-value Score Description name (Pfam, InterPro, SMART) length from to Tropomyosin_1 (PF12718, IPR000533) 143 8 154 5.1e-38 116.600 Tropomyosin like Tropomyosin (PF00261, IPR000533) 237 49 282 1.9e-84 268.800 Tropomyosin SlyX (PF04102, IPR007236) 67 236 295 0.0008 6.400 SlyX Pkinase_Tyr (PF07714, IPR001245) 260 317 584 2.5e-93 298.200 Protein tyrosine kinase Updated: 2019-02-20 Owner: ChiTaRS	TPM3 A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4G8 A0A0S2Z4I4 A0A2R2Y2Q3 A0A494C034 A0A494C0G0 A0A494C0P6 D6R904 D6RGJ6 J3KN67 P06753 Q5HYB6 Q5VU61 Q5VU62 Q8NAH0 Q8NI98 NM_001278189.1	12..220 97.2%	- 1	ALK A0A024A2P5 A0A087WZL3 A0A097F6U9 A0A0K2YUJ3 B2MXD7 B2MXD8 B2MXD9 B2MXE0 B2MXE1 B2MXE2 B2MXE3 B2MXE4 B2MXE5 B2MXE6 B2MXE7 B6D4Y1 B6D4Y2 B6D4Y3 B6D4Y5 B6D4Y6 B6D4Y7 B6D4Y8 D1MAM0 D1MAM1 D1MAM2 D1MAM3 D1MAM4 D1MAM5 E7EPW7 F0UY65 F0UY66 H7BZ33 Q580I3 Q9UM73 NM_004304.4	212..308 96.9%	- 2	0 65535 7298	exon-exon		BREAKPOINTs more info 10216106 10610119 10934142 12707379 24445538 24875859 26647767 26773439 26892443 29329131 29405994
8 Homo Sapiens	JB625501 ANNOTATION OF CHIMERA FUSION GenBank ID: JB625501 FASTA Head Gene (1) Alignment: TPM3 | OMIM: 191030 Tail Gene (2) Alignment: ROS1 | OMIM: 165020 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 7170 1 - 154170400 154192018 8 1 oncogene 6098 6 - 117288492 117321396 9 1 oncogene 2178 hg38 Updated: 2019-06-02 Owner: ChiTaRS	TPM3 A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4G8 A0A0S2Z4I4 A0A2R2Y2Q3 A0A494C034 A0A494C0G0 A0A494C0P6 D6R904 D6RGJ6 J3KN67 P06753 Q5HYB6 Q5VU61 Q5VU62 Q8NAH0 Q8NI98 NM_152263.3	1..775 100.0%	- 1	ROS1 H0Y3T9 P08922 Q5H8Y1 XM_011536049.2	774..2178 100.0%	- 6	1 0 0	exon-exon		BREAKPOINTs more info 22327623 22327623 24445538 25742289
9 Homo Sapiens	EC445019 ANNOTATION OF CHIMERA FUSION GenBank ID: EC445019 FASTA Head Gene (1) Alignment: TPM3 | OMIM: 191030 Tail Gene (2) Alignment: TPM3 | OMIM: 191030 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 7170 1 - 154157100 154157136 1 1 oncogene 7170 1 + 154157138 154157219 1 1 oncogene 116 hg38 Updated: 2019-04-14 Owner: ChiTaRS	TPM3 A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4G8 A0A0S2Z4I4 A0A2R2Y2Q3 A0A494C034 A0A494C0G0 A0A494C0P6 D6R904 D6RGJ6 J3KN67 P06753 Q5HYB6 Q5VU61 Q5VU62 Q8NAH0 Q8NI98 NM_001349679.1	1..37 100.0%	- 1	TPM3 A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4G8 A0A0S2Z4I4 A0A2R2Y2Q3 A0A494C034 A0A494C0G0 A0A494C0P6 D6R904 D6RGJ6 J3KN67 P06753 Q5HYB6 Q5VU61 Q5VU62 Q8NAH0 Q8NI98 NM_001349679.1	35..116 100.0%	+ 1	0 1518 1523	exon-exon	3HiC Hi-C contacts of chimeric junction Fusion Gene1 chromosome1 junction start1 junction end1 Hi-C point1 Δ1 Gene2 chromosome2 junction start2 junction end2 Hi-C point2 Δ2 Cell lines (Cellosaurus ID) 2 3 19 - - 32 - 8 25 - - 33 - 34 EC445019 TPM3 1 154157134 154157136 154147524 9610 TPM3 1 154157138 154157140 154147524 9614 GM12878 (CVCL_7526), KBM-7 (CVCL_A426), epiHUVEC (CVCL_9S75) EC445019 TPM3 1 154157134 154157136 154147524 9610 TPM3 1 154157138 154157140 154157524 384 GM12878 (CVCL_7526), KBM-7 (CVCL_A426) EC445019 TPM3 1 154157134 154157136 154157524 388 TPM3 1 154157138 154157140 154157524 384 GM12878 (CVCL_7526), KBM-7 (CVCL_A426)
10 Homo Sapiens	DL051249 ANNOTATION OF CHIMERA FUSION GenBank ID: DL051249 FASTA Head Gene (1) Alignment: TPM3 | OMIM: 191030 Tail Gene (2) Alignment: TPM3 | OMIM: 191030 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 7170 1 + 154155615 154155637 1 1 oncogene 7170 1 - 154155308 154155618 9 1 oncogene 340 hg38 Domains of the full fusion Envelope E-value Score Description name (Pfam, InterPro, SMART) length from to Tropomyosin (PF00261, IPR000533) 237 55 223 3.3e-62 196.100 Tropomyosin Updated: 2019-02-17 Owner: ChiTaRS	TPM3 A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4G8 A0A0S2Z4I4 A0A2R2Y2Q3 A0A494C034 A0A494C0G0 A0A494C0P6 D6R904 D6RGJ6 J3KN67 P06753 Q5HYB6 Q5VU61 Q5VU62 Q8NAH0 Q8NI98 NM_001278189.1	9..31 100.0%	+ 1	TPM3 A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4G8 A0A0S2Z4I4 A0A2R2Y2Q3 A0A494C034 A0A494C0G0 A0A494C0P6 D6R904 D6RGJ6 J3KN67 P06753 Q5HYB6 Q5VU61 Q5VU62 Q8NAH0 Q8NI98 NM_001278189.1	29..340 97.8%	- 1	1 0 0	exon-exon	3HiC Hi-C contacts of chimeric junction Fusion Gene1 chromosome1 junction start1 junction end1 Hi-C point1 Δ1 Gene2 chromosome2 junction start2 junction end2 Hi-C point2 Δ2 Cell lines (Cellosaurus ID) 2 3 19 - - 32 - 8 25 - - 33 - 34 DL051249 TPM3 1 154155635 154155637 154147524 8111 TPM3 1 154155308 154155310 154147524 7784 GM12878 (CVCL_7526), KBM-7 (CVCL_A426), epiHUVEC (CVCL_9S75) DL051249 TPM3 1 154155635 154155637 154157524 1887 TPM3 1 154155308 154155310 154147524 7784 GM12878 (CVCL_7526), KBM-7 (CVCL_A426) DL051249 TPM3 1 154155635 154155637 154157524 1887 TPM3 1 154155308 154155310 154157524 2214 GM12878 (CVCL_7526), KBM-7 (CVCL_A426)

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