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Rank: Junction Consistence: Hi-C Sense-ANTIsense

Mass-spec hits Read-through chimeras Breakpoints RNAseq evidence
UniProtKB hits
Organisms
Homo Sapiens Mus musculus D.Melanogaster
Rattus Norvegicus Bos Taurus Danio Rerio
Saccharomyces Cerevisiae Sus ScrofaAll organisms

Result for the search of Gene Name/NCBI ID(s): 'RBPJ'

Total of fusion sequences: 21 (from 1493742 parsed EST/mRNAs. Last update 2019-12-11 12:04:16)

Organism Fusion:
Graphical View,
Annotation,
PPI network 		Head Gene (1) Tail Gene (2) Rank,
Deviation:
Eloc(x)
Sloc(y) 		Fusion type RNA Hi-C,
RNAseq,
Mass-spec
evidences		 Cancer
Breakpoint,
PubMed(s)
Name(s)1,
transcript		 Start1..End1
Ident1% 		Strand1
Chrom1 		Name(s)2,
transcript		 Start2..End2
Ident2% 		Strand2
Chrom2
1234,5,67,1989,10,1112,2513,14,15321617
1
Homo Sapiens		SplGraphs

ANNOTATION OF CHIMERA FUSION

GenBank ID: AU125113 FASTA
Head Gene (1) Alignment: RBPJ | OMIM: 147183 Tail Gene (2) Alignment: GLB1 | OMIM: 611458 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
35164+2643349726433737121protein-coding27203-3302425133097118121oncogene 851 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
LAG1-DNAbind (PF09271, IPR015351) 152 170 300 1.8e-54 170.700 LAG1, DNA binding
BTD (PF09270, IPR015350) 153 301 450 4.5e-78 247.000 Beta-trefoil DNA-binding domain
TIG (PF01833, IPR002909) 85 477 566 5.2e-07 16.000 IPT/TIG domain
BetaGal_dom4_5 (PF13364, IPR025300) 114 1722 1813 0.053 0.400 Beta-galactosidase jelly roll domain
Updated: 2019-02-20
Owner: ChiTaRS
NM_005349.3		38..278
99.2%		+
4
NM_001317040.1		278..794
99.3%		-
3		1
0
0		exon-exon
2
Homo Sapiens		 ChimerDB

ANNOTATION OF CHIMERA FUSION

GenBank ID: DC301955 FASTA
Head Gene (1) Alignment: TEKT4P2 Tail Gene (2) Alignment: RBPJ | OMIM: 147183 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
10013228821-9127489912982540pseudo35164+2636244526406244111protein-coding 584 hg38
Updated: 2019-02-02
Owner: ChiTaRS
TEKT4P2
NR_038328.2		91..292
97.3%		-
21
XM_024454032.1		292..584
100.0%		+
4		1
0
0		intron-exon
3
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: BM994447 FASTA
Head Gene (1) Alignment: RBPJ | OMIM: 147183 Tail Gene (2) Alignment: RBPJ | OMIM: 147183 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
35164-2643082126431202131protein-coding35164+264307422643083611protein-coding 489 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
LAG1-DNAbind (PF09271, IPR015351) 152 48 178 4.3e-55 172.700 LAG1, DNA binding
BTD (PF09270, IPR015350) 153 179 328 1e-78 249.000 Beta-trefoil DNA-binding domain
TIG (PF01833, IPR002909) 85 355 444 1.4e-07 17.800 IPT/TIG domain
RHD_dimer (PF16179, IPR032397) 103 630 662 2.2e-05 10.800 Rel homology dimerisation domain
Updated: 2019-02-21
Owner: ChiTaRS
XM_024454032.1		1..381
100.0%		-
4
XM_024454032.1		378..472
100.0%		+
4		1
0
0		exon-exon

Hi-C contacts of chimeric junction

Fusion Gene1 chromo-
some1		 junction start1 junction end1 Hi-C point1 Δ1 Gene2 chromo-
some2		 junction start2 junction end2 Hi-C point2 Δ2 Cell lines
(Cell_ID,)		 PubMed(,s)
2319--32-825--33-34-
BM994447 RBPJ 4 26431199 26431202 26428378 2821 RBPJ 4 26430742 26430745 26428378 2364 IMR-90 (CVCL_0347) 25497547
BM994447 RBPJ 4 26431199 26431202 26438378 7176 RBPJ 4 26430742 26430745 26428378 2364 NHEK/SV3 (CVCL_9Q50) 25497547
BM994447 RBPJ 4 26431199 26431202 26438378 7176 RBPJ 4 26430742 26430745 26438378 7633 NHEK/SV3 (CVCL_9Q50) 25497547
4
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: NM_024096 FASTA
UniProtKB: Q9H773 dCTP pyrophosphatase 1 (EC 3.6.1.12) (Deoxycytidine-triphosphatase 1) (dCTPase 1) (RS21C6) (XTP3-transactivated gene A protein)
Fusion Gene(s): DCTPP1 XTP3TPA CDA03
Head Gene (1) Alignment: DCTPP1 | OMIM: 615840 Tail Gene (2) Alignment: RBPJ | OMIM: 147183 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
7907716-304236983043005231protein-coding35164-262469742624746600protein-coding 1143 hg38
Updated: 2019-03-25
Owner: ChiTaRS
NR_134470.1		1..1120
100.0%		-
16
XM_024454032.1		1071..1143
97.5%		-
4		1
0
0		exon-intron
5
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AV691001 FASTA
Head Gene (1) Alignment: RBPJ | OMIM: 147183 Tail Gene (2) Alignment: IDH1 | OMIM: 147700 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
35164+262746272627496810protein-coding34172-20824244420824278860oncogene,
tumor suppressor		 369 hg38
Updated: 2019-02-01
Owner: ChiTaRS
XM_005248161.4		11..57
97.9%		+
4
NM_001282387.1		22..363
100.0%		-
2		1
0
0		intron-intron
6
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AV688879 FASTA
Head Gene (1) Alignment: RBPJ | OMIM: 147183 Tail Gene (2) Alignment: IDH1 | OMIM: 147700 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
35164+262746272627496810protein-coding34172-20824244420824278860oncogene,
tumor suppressor		 369 hg38
Updated: 2019-02-01
Owner: ChiTaRS
XM_005248161.4		11..57
97.9%		+
4
NM_001282387.1		22..363
100.0%		-
2		1
0
0		intron-intron
7
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AV686462 FASTA
Head Gene (1) Alignment: RBPJ | OMIM: 147183 Tail Gene (2) Alignment: IDH1 | OMIM: 147700 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
35164+262746272627496810protein-coding34172-20824244420824278860oncogene,
tumor suppressor		 369 hg38
Updated: 2019-02-01
Owner: ChiTaRS
XM_005248161.4		11..57
97.9%		+
4
NM_001282387.1		22..363
100.0%		-
2		1
0
0		intron-intron
8
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AV685560 FASTA
Head Gene (1) Alignment: RBPJ | OMIM: 147183 Tail Gene (2) Alignment: IDH1 | OMIM: 147700 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
35164+262746272627496810protein-coding34172-20824244420824278860oncogene,
tumor suppressor		 369 hg38
Updated: 2019-02-01
Owner: ChiTaRS
XM_005248161.4		11..57
97.9%		+
4
NM_001282387.1		22..363
100.0%		-
2		1
0
0		intron-intron
9
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AV685353 FASTA
Head Gene (1) Alignment: RBPJ | OMIM: 147183 Tail Gene (2) Alignment: IDH1 | OMIM: 147700 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
35164+262746272627496810protein-coding34172-20824244420824278860oncogene,
tumor suppressor		 369 hg38
Updated: 2019-02-01
Owner: ChiTaRS
XM_005248161.4		11..57
97.9%		+
4
NM_001282387.1		22..363
100.0%		-
2		1
0
0		intron-intron
10
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: FN103232 FASTA
Head Gene (1) Alignment: ANKRD52 Tail Gene (2) Alignment: RBPJ | OMIM: 147183 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
28337312-562420555624251211protein-coding35164+264300112643046831protein-coding 100 hg38
Updated: 2019-02-07
Owner: ChiTaRS
NM_173595.3		1..25
100.0%		-
12
XM_024454032.1		6..96
95.7%		+
4		1
0
0		exon-exon

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