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Rank: Junction Consistence: Hi-C Sense-ANTIsense

Mass-spec hits Read-through chimeras Breakpoints RNAseq evidence
UniProtKB hits
Organisms
Homo Sapiens Mus musculus D.Melanogaster
Rattus Norvegicus Bos Taurus Danio Rerio
Saccharomyces Cerevisiae Sus ScrofaAll organisms

Result for the search of Gene Name/NCBI ID(s): 'Nfat5'

Total of fusion sequences: 35 (from 3,568,812 parsed EST/mRNAs. Last update: 2020-07-14 10:36:55)

Organism Fusion:
Graphical View,
Annotation,
PPI network 		Head Gene (1) Tail Gene (2) Rank,
Deviation:
Eloc(x)
Sloc(y) 		Fusion type RNA Hi-C,
RNAseq,
Mass-spec
evidences		 Cancer
Breakpoint,
PubMed(s)
Name(s)1,
transcript		 Start1..End1
Ident1% 		Strand1
Chrom1 		Name(s)2,
transcript		 Start2..End2
Ident2% 		Strand2
Chrom2
1234,5,67,1989,10,1112,2513,14,15321617
1
Homo Sapiens		 ChimerDB

ANNOTATION OF CHIMERA FUSION

GenBank ID: BQ322337 FASTA
Head Gene (1) Alignment: CCND1 | OMIM: 168461 Tail Gene (2) Alignment: NFAT5 | OMIM: 604708 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
59511-696531596965326451oncogene,
protein-coding		1072516+697037366970388911oncogene,
protein-coding		 250 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Cyclin_N (PF00134, IPR006671) 127 101 228 3.5e-41 126.200 Cyclin, N-terminal domain
Cyclin_C (PF02984, IPR004367) 119 230 357 1.2e-23 69.700 Cyclin, C-terminal domain
Updated: 2019-02-21
Owner: ChiTaRS
NM_053056.2		1..103
97.1%		-
11
NM_138714.3		97..250
100.0%		+
16		1
0
0		exon-exon
2
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: EC557388 FASTA
Head Gene (1) Alignment: WWP2 | OMIM: 602308 Tail Gene (2) Alignment: NFAT5 | OMIM: 604708 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
1106016-698250406983285100protein-coding1072516-696171666961721900oncogene,
protein-coding		 104 hg38
Updated: 2019-03-25
Owner: ChiTaRS
XM_017022880.1		14..50
96.8%		-
16
XM_011522819.3		51..104
96.8%		-
16		1
0
0		intron-intron

Hi-C contacts of chimeric junction

Fusion Gene1 chromo-
some1		 junction start1 junction end1 Hi-C point1 Δ1 Gene2 chromo-
some2		 junction start2 junction end2 Hi-C point2 Δ2 Cell lines
(Cell_ID,)		 PubMed(,s)
2319--32-825--33-34-
EC557388 WWP2 16 69832850 69832851 69826097 6753 NFAT5 16 69617166 69617167 69616097 1069 HUVEC-C (CVCL_2959) 25497547
EC557388 WWP2 16 69832850 69832851 69836097 3246 NFAT5 16 69617166 69617167 69616097 1069 KBM-7 (CVCL_A426) 25497547
EC557388 WWP2 16 69832850 69832851 69826097 6753 NFAT5 16 69617166 69617167 69626097 8930 HUVEC-C (CVCL_2959) 25497547
EC557388 WWP2 16 69832850 69832851 69836097 3246 NFAT5 16 69617166 69617167 69626097 8930 KBM-7 (CVCL_A426) 25497547
BREAKPOINTs
29099951
3
Mus musculus

ANNOTATION OF CHIMERA FUSION

GenBank ID: AK134022 FASTA
UniProtKB: Q3UZ77 Uncharacterized protein
Fusion Gene(s): Nfat5
Head Gene (1) Alignment: Nfat5 Tail Gene (2) Alignment: Zfhx3 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
544468+107293470107358767121protein-coding119068-10882540610882565500protein-coding 2360 mm10
Updated: 2019-05-28
Owner: ChiTaRS
XM_006531194.2		2..2113
99.9%		+
8
NM_007496.2		2111..2360
100.0%		-
8		1
0
0		exon-intron

Hi-C contacts of chimeric junction

Fusion Gene1 chromo-
some1		 junction start1 junction end1 Hi-C point1 Δ1 Gene2 chromo-
some2		 junction start2 junction end2 Hi-C point2 Δ2 Cell lines
(Cell_ID,)		 PubMed(,s)
2319--32-825--33-34-
AK134022 Nfat5 8 107358765 107358767 107350000 8765 Zfhx3 8 108825406 108825408 108820000 5406 ES-C57BL/6 (CVCL_5746) 28802249
AK134022 Nfat5 8 107358765 107358767 107350000 8765 Zfhx3 8 108825406 108825408 108830000 4592 Patski (CVCL_Y494), ES-C57BL/6 (CVCL_5746) 27432957, 28802249
AK134022 Nfat5 8 107358765 107358767 107360000 1233 Zfhx3 8 108825406 108825408 108820000 5406 ES-C57BL/6 (CVCL_5746) 28802249
AK134022 Nfat5 8 107358765 107358767 107360000 1233 Zfhx3 8 108825406 108825408 108830000 4592 Patski (CVCL_Y494), ES-C57BL/6 (CVCL_5746) 27432957, 28802249
4
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: BF856225 FASTA
Head Gene (1) Alignment: NFAT5 | OMIM: 604708 Tail Gene (2) Alignment: NFAT5 | OMIM: 604708 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
1072516-695902156959030400oncogene,
protein-coding		1072516+695901306959026600oncogene,
protein-coding		 235 hg38
Updated: 2019-04-10
Owner: ChiTaRS
XM_011522819.3		1..90
98.9%		-
16
XM_011522819.3		88..225
97.1%		+
16		0
65535
65535		intron-intron

Hi-C contacts of chimeric junction

Fusion Gene1 chromo-
some1		 junction start1 junction end1 Hi-C point1 Δ1 Gene2 chromo-
some2		 junction start2 junction end2 Hi-C point2 Δ2 Cell lines
(Cell_ID,)		 PubMed(,s)
2319--32-825--33-34-
BF856225 NFAT5 16 69590302 69590304 69586097 4205 NFAT5 16 69590130 69590132 69586097 4033 hTERT-RPE1 (CVCL_4388) 27432957
BF856225 NFAT5 16 69590302 69590304 69596097 5793 NFAT5 16 69590130 69590132 69596097 5965 NHEK/SV3 (CVCL_9Q50) 25497547
5
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: BQ373253 FASTA
Head Gene (1) Alignment: NFAT5 | OMIM: 604708 Tail Gene (2) Alignment: NFAT5 | OMIM: 604708 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
1072516-697027976970284611oncogene,
protein-coding		1072516+697027206970279611oncogene,
protein-coding		 120 hg38
Updated: 2019-04-10
Owner: ChiTaRS
NM_138714.3		1..47
95.6%		-
16
NM_138714.3		44..120
100.0%		+
16		0
12471
10814		exon-exon

Hi-C contacts of chimeric junction

Fusion Gene1 chromo-
some1		 junction start1 junction end1 Hi-C point1 Δ1 Gene2 chromo-
some2		 junction start2 junction end2 Hi-C point2 Δ2 Cell lines
(Cell_ID,)		 PubMed(,s)
2319--32-825--33-34-
BQ373253 NFAT5 16 69702843 69702846 69696097 6746 NFAT5 16 69702720 69702723 69696097 6623 HMEC-1 (CVCL_0307) 25497547
6
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AA700302 FASTA
Head Gene (1) Alignment: NFAT5 | OMIM: 604708 Tail Gene (2) Alignment: NFAT5 | OMIM: 604708 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
1072516-6968983169690096130oncogene,
protein-coding		1072516-696919216969211531oncogene,
protein-coding		 455 hg38
Updated: 2019-02-20
Owner: ChiTaRS
XM_011522818.3		1..266
100.0%		-
16
XM_011522818.3		261..455
99.5%		-
16		2
229
62		intron-exon

Hi-C contacts of chimeric junction

Fusion Gene1 chromo-
some1		 junction start1 junction end1 Hi-C point1 Δ1 Gene2 chromo-
some2		 junction start2 junction end2 Hi-C point2 Δ2 Cell lines
(Cell_ID,)		 PubMed(,s)
2319--32-825--33-34-
AA700302 NFAT5 16 69690091 69690096 69686097 3994 NFAT5 16 69691921 69691926 69686097 5824 WA01 (CVCL_9771) 22495300
AA700302 NFAT5 16 69690091 69690096 69686097 3994 NFAT5 16 69691921 69691926 69696097 4171 HMEC-1 (CVCL_0307) 25497547
AA700302 NFAT5 16 69690091 69690096 69696097 6001 NFAT5 16 69691921 69691926 69696097 4171 HMEC-1 (CVCL_0307) 25497547
7
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AA694235 FASTA
Head Gene (1) Alignment: NFAT5 | OMIM: 604708 Tail Gene (2) Alignment: NFAT5 | OMIM: 604708 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
1072516-6968983169690325130oncogene,
protein-coding		1072516-696919836969211531oncogene,
protein-coding		 432 hg38
Updated: 2019-02-20
Owner: ChiTaRS
XM_011522818.3		1..305
100.0%		-
16
XM_011522818.3		300..432
100.0%		-
16		2
229
62		intron-exon

Hi-C contacts of chimeric junction

Fusion Gene1 chromo-
some1		 junction start1 junction end1 Hi-C point1 Δ1 Gene2 chromo-
some2		 junction start2 junction end2 Hi-C point2 Δ2 Cell lines
(Cell_ID,)		 PubMed(,s)
2319--32-825--33-34-
AA694235 NFAT5 16 69690320 69690325 69686097 4223 NFAT5 16 69691983 69691988 69686097 5886 WA01 (CVCL_9771) 22495300
AA694235 NFAT5 16 69690320 69690325 69686097 4223 NFAT5 16 69691983 69691988 69696097 4109 HMEC-1 (CVCL_0307) 25497547
AA694235 NFAT5 16 69690320 69690325 69696097 5772 NFAT5 16 69691983 69691988 69696097 4109 HMEC-1 (CVCL_0307) 25497547
8
Mus musculus

ANNOTATION OF CHIMERA FUSION

GenBank ID: BC050750 FASTA
UniProtKB: Q80X68 Citrate synthase
Fusion Gene(s): Csl mCG_19869
Head Gene (1) Alignment: Csl Tail Gene (2) Alignment: Nfat5 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
7183210-997577069975945611544468+10729320010729322711protein-coding 1782 mm10
Updated: 2019-06-16
Owner: ChiTaRS
NM_027945.3		1..1751
100.0%		-
10
XM_006531193.3		1749..1776
100.0%		+
8		1
0
0		exon-exon
9
Mus musculus

ANNOTATION OF CHIMERA FUSION

GenBank ID: BC043659 FASTA
UniProtKB: Q80XN5 Usp52 protein
Fusion Gene(s): Pan2 Usp52
Head Gene (1) Alignment: Pan2 Tail Gene (2) Alignment: Nfat5 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
10313510+128314196128321353141protein-coding544468-10737111110737113200protein-coding 2385 mm10
Updated: 2019-06-16
Owner: ChiTaRS
XR_380328.1		1..2360
100.0%		+
10
XM_006531194.2		2346..2367
95.5%		-
8		1
0
0		exon-intron
10
Mus musculus

ANNOTATION OF CHIMERA FUSION

GenBank ID: AY050663 FASTA
UniProtKB: Q8VHJ6 Nuclear factor of activated T-cells 5 (Transcription factor NFAT5)
Fusion Gene(s): Nfat5
Head Gene (1) Alignment: Nfat5 Tail Gene (2) Alignment: Rem1 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
544468+107293862107372227171protein-coding197002+15263497515263519811 5992 mm10
Updated: 2019-05-28
Owner: ChiTaRS
XM_006531194.2		1..5756
99.7%		+
8
NM_009047.5		5749..5973
96.5%		+
2		1
0
0		exon-exon

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