Result for the search of Gene Name/NCBI ID(s): 'LRP6'

Total of fusion sequences: 12 (from 10,657,267 parsed EST/mRNAs. Last update: 2020-11-05 10:39:19)

Organism	Fusion: Graphical View, Annotation, PPI network	Head Gene (1)			Tail Gene (2)			Rank, Deviation: Eloc(x) Sloc(y)	Fusion type RNA	Hi-C, RNAseq, Mass-spec evidences	Cancer Breakpoint, PubMed(s)
		Name(s)1, transcript	Start1..End1 Ident1%	Strand1 Chrom1	Name(s)2, transcript	Start2..End2 Ident2%	Strand2 Chrom2
1	2	3	4,5,6	7,19	8	9,10,11	12,25	13,14,15	32	16	17
1 Homo Sapiens	ChimerDB AW205111 ANNOTATION OF CHIMERA FUSION GenBank ID: AW205111 FASTA Head Gene (1) Alignment: C5orf66 Tail Gene (2) Alignment: LRP6 | OMIM: 603507 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 100996485 5 + 135334381 135334600 4 0 protein-coding, ncRNA 4040 12 + 12121013 12121149 23 1 protein-coding 368 hg38 Updated: 2019-02-02 Owner: ChiTaRS	C5orf66 Q9H5L9 NM_001277348.1	18..237 99.6%	+ 5	LRP6 B7ZLD0 F5H0Z3 F5H7J9 H0YGH0 H0YGW5 O75581 XR_002957325.1	232..368 99.3%	+ 12	1 0 0	intron-exon
2 Homo Sapiens	AW021548 ANNOTATION OF CHIMERA FUSION GenBank ID: AW021548 FASTA Head Gene (1) Alignment: LRP6 | OMIM: 603507 Tail Gene (2) Alignment: LRP6 | OMIM: 603507 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 4040 12 + 12116536 12116564 1 1 protein-coding 4040 12 - 12116025 12116537 24 1 protein-coding 572 hg38 Updated: 2019-02-07 Owner: ChiTaRS	LRP6 B7ZLD0 F5H0Z3 F5H7J9 H0YGH0 H0YGW5 O75581 XR_429035.3	8..36 100.0%	+ 12	LRP6 B7ZLD0 F5H0Z3 F5H7J9 H0YGH0 H0YGW5 O75581 XR_002957325.1	30..542 100.0%	- 12	2 27 511	exon-exon	1HiC Hi-C contacts of chimeric junction Fusion Gene1 chromo- some1 junction start1 junction end1 Hi-C point1 Δ1 Gene2 chromo- some2 junction start2 junction end2 Hi-C point2 Δ2 Cell lines (Cell_ID,) PubMed(,s) 2 3 19 - - 32 - 8 25 - - 33 - 34 - AW021548 LRP6 12 12116558 12116564 12117066 502 LRP6 12 12116025 12116031 12117066 1035 GM12878 (CVCL_7526) 25497547
3 Homo Sapiens	BI492505 ANNOTATION OF CHIMERA FUSION GenBank ID: BI492505 FASTA Head Gene (1) Alignment: LRP6 | OMIM: 603507 Tail Gene (2) Alignment: LRP6 | OMIM: 603507 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 4040 12 + 12116025 12116537 1 1 protein-coding 4040 12 - 12116536 12116564 25 1 protein-coding 544 hg38 Updated: 2019-02-17 Owner: ChiTaRS	LRP6 B7ZLD0 F5H0Z3 F5H7J9 H0YGH0 H0YGW5 O75581 XR_429035.3	3..515 100.0%	+ 12	LRP6 B7ZLD0 F5H0Z3 F5H7J9 H0YGH0 H0YGW5 O75581 XR_429035.3	509..537 100.0%	- 12	2 27 511	exon-exon	1HiC Hi-C contacts of chimeric junction Fusion Gene1 chromo- some1 junction start1 junction end1 Hi-C point1 Δ1 Gene2 chromo- some2 junction start2 junction end2 Hi-C point2 Δ2 Cell lines (Cell_ID,) PubMed(,s) 2 3 19 - - 32 - 8 25 - - 33 - 34 - BI492505 LRP6 12 12116531 12116537 12117066 529 LRP6 12 12116536 12116542 12117066 524 GM12878 (CVCL_7526) 25497547
4 Homo Sapiens	BE067646 ANNOTATION OF CHIMERA FUSION GenBank ID: BE067646 FASTA Head Gene (1) Alignment: TOX3 | OMIM: 611416 Tail Gene (2) Alignment: LRP6 | OMIM: 603507 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 27324 16 + 52519415 52519527 7 1 protein-coding 4040 12 + 12248086 12248212 1 0 protein-coding 226 hg38 Domains of the full fusion Envelope E-value Score Description name (Pfam, InterPro, SMART) length from to Ldl_recept_b (PF00058, IPR000033, SM00135) 42 223 264 2.8e-07 17.300 Low-density lipoprotein receptor repeat class B FXa_inhibition (PF14670) 36 446 483 3.3e-15 42.500 Coagulation Factor Xa inhibitory site DUF5050 (PF16472, IPR032485) 282 1100 1271 1.1e-05 10.900 Domain of unknown function (DUF5050) Ldl_recept_a (PF00057, IPR002172, SM00192) 37 1401 1437 6.9e-15 41.400 Low-density lipoprotein receptor domain class A Updated: 2019-02-20 Owner: ChiTaRS	TOX3 H3BTZ9 J3QQQ6 O15405 NM_001146188.2	5..114 97.3%	+ 16	LRP6 B7ZLD0 F5H0Z3 F5H7J9 H0YGH0 H0YGW5 O75581 XR_429035.3	99..226 97.7%	+ 12	2 0 32	exon-intron
5 Homo Sapiens	BE067643 ANNOTATION OF CHIMERA FUSION GenBank ID: BE067643 FASTA Head Gene (1) Alignment: TOX3 | OMIM: 611416 Tail Gene (2) Alignment: LRP6 | OMIM: 603507 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 27324 16 + 52519447 52519527 7 1 protein-coding 4040 12 + 12248086 12248212 1 0 protein-coding 192 hg38 Domains of the full fusion Envelope E-value Score Description name (Pfam, InterPro, SMART) length from to Ldl_recept_b (PF00058, IPR000033, SM00135) 42 203 244 6e-07 16.200 Low-density lipoprotein receptor repeat class B FXa_inhibition (PF14670) 36 426 463 7e-15 41.400 Coagulation Factor Xa inhibitory site DUF5050 (PF16472, IPR032485) 282 1149 1248 3.5e-05 9.300 Domain of unknown function (DUF5050) Ldl_recept_a (PF00057, IPR002172, SM00192) 37 1387 1425 7.6e-15 41.200 Low-density lipoprotein receptor domain class A Updated: 2019-02-20 Owner: ChiTaRS	TOX3 H3BTZ9 J3QQQ6 O15405 NM_001146188.2	1..81 97.5%	+ 16	LRP6 B7ZLD0 F5H0Z3 F5H7J9 H0YGH0 H0YGW5 O75581 XR_429035.3	66..192 100.0%	+ 12	2 0 32	exon-intron
6 Homo Sapiens	DN916020 ANNOTATION OF CHIMERA FUSION GenBank ID: DN916020 FASTA Head Gene (1) Alignment: PRKAR1A | OMIM: 188830 Tail Gene (2) Alignment: LRP6 | OMIM: 603507 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 5573 17 - 68483908 68483942 0 0 oncogene, tumor suppressor, protein-coding 4040 12 + 12143556 12143940 0 0 protein-coding 403 hg38 Updated: 2019-03-25 Owner: ChiTaRS	PRKAR1A A1XGZ0 B2R5T5 K7EID3 K7EIE5 K7EJ40 K7EK41 K7EKR1 K7EM13 K7EMU2 K7EMZ6 K7EPB2 K7EPR5 K7EQK3 P10644 Q96P62 X6RAV4 XM_011524984.3	12..43 96.8%	- 17	LRP6 B7ZLD0 F5H0Z3 F5H7J9 H0YGH0 H0YGW5 O75581 XR_429035.3	19..403 100.0%	+ 12	1 0 0	intron-intron
7 Homo Sapiens	DN916021 ANNOTATION OF CHIMERA FUSION GenBank ID: DN916021 FASTA Head Gene (1) Alignment: LRP6 | OMIM: 603507 Tail Gene (2) Alignment: PRKAR1A | OMIM: 188830 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 4040 12 - 12143556 12143940 0 0 protein-coding 5573 17 + 68483908 68483942 0 0 oncogene, tumor suppressor, protein-coding 403 hg38 Updated: 2019-03-25 Owner: ChiTaRS	LRP6 B7ZLD0 F5H0Z3 F5H7J9 H0YGH0 H0YGW5 O75581 XR_429035.3	1..385 100.0%	- 12	PRKAR1A A1XGZ0 B2R5T5 K7EID3 K7EIE5 K7EJ40 K7EK41 K7EKR1 K7EM13 K7EMU2 K7EMZ6 K7EPB2 K7EPR5 K7EQK3 P10644 Q96P62 X6RAV4 XM_011524984.3	361..392 96.8%	+ 17	1 0 0	intron-intron
8 Homo Sapiens	CD644157 ANNOTATION OF CHIMERA FUSION GenBank ID: CD644157 FASTA Head Gene (1) Alignment: LRP6 | OMIM: 603507 Tail Gene (2) Alignment: LRBA | OMIM: 606453 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 4040 12 - 12120536 12121729 3 0 protein-coding 987 4 - 150992496 150992527 2 0 oncogene, protein-coding 854 hg38 Updated: 2019-02-17 Owner: ChiTaRS	LRP6 B7ZLD0 F5H0Z3 F5H7J9 H0YGH0 H0YGW5 O75581 XR_429035.3	11..795 99.2%	- 12	LRBA A0A3B3IS13 A0A3B3ISK3 A0A3B3IU76 A0A494BZW2 A0A494C0R9 A0A494C1L5 E9PEM5 H0Y9N9 H0YA17 H0YAC6 P50851 Q6P1X2 Q969R7 XM_005263372.3	777..802 100.0%	- 4	1 0 0	intron-intron
9 Homo Sapiens	BI496183 ANNOTATION OF CHIMERA FUSION GenBank ID: BI496183 FASTA Head Gene (1) Alignment: LRP6 | OMIM: 603507 Tail Gene (2) Alignment: HNRNPA1P48 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 4040 12 - 12163635 12164153 16 0 protein-coding 642659 16 - 51646985 51647132 1 1 pseudo 173 hg38 Updated: 2019-02-17 Owner: ChiTaRS	LRP6 B7ZLD0 F5H0Z3 F5H7J9 H0YGH0 H0YGW5 O75581 XR_429035.3	8..43 97.3%	- 12	HNRNPA1P48 A0A2R8Y4L2	21..166 98.7%	- 16	1 0 0	intron-exon
10 Homo Sapiens	AX379005 ANNOTATION OF CHIMERA FUSION GenBank ID: AX379005 FASTA Head Gene (1) Alignment: LRP6 | OMIM: 603507 Tail Gene (2) Alignment: ODC1 | OMIM: 165640 Qsize UCSC Version Location: exons highlight1 Location: exons highlight2 Entrez GeneID1 chromo- some1 strand1 start_loc1 end_loc1 total1 overlap1 Entrez GeneID2 chromo- some2 strand2 start_loc2 end_loc2 total2 overlap2 18 19 7 20 21 22 23 - 24 25 12 26 27 28 29 - 30 31 4040 12 - 12116595 12116957 1 1 protein-coding 4953 2 - 10440410 10440479 12 1 protein-coding 425 hg38 Updated: 2019-01-31 Owner: ChiTaRS	LRP6 B7ZLD0 F5H0Z3 F5H7J9 H0YGH0 H0YGW5 O75581 XR_429035.3	1..363 100.0%	- 12	ODC1 C9JG30 L8EA08 P11926 NM_001287188.1	356..425 100.0%	- 2	1 0 0	exon-exon

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