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Rank: Junction Consistence: Hi-C Sense-ANTIsense

Mass-spec hits Read-through chimeras Breakpoints RNAseq evidence
UniProtKB hits
Organisms
Homo Sapiens Mus musculus D.Melanogaster
Rattus Norvegicus Bos Taurus Danio Rerio
Saccharomyces Cerevisiae Sus ScrofaAll organisms

Result for the search of Gene Name/NCBI ID(s): 'Hk2'

Total of fusion sequences: 2 (from 3,531,238 parsed EST/mRNAs. Last update: 2020-07-10 14:21:01)

Organism Fusion:
Graphical View,
Annotation,
PPI network 		Head Gene (1) Tail Gene (2) Rank,
Deviation:
Eloc(x)
Sloc(y) 		Fusion type RNA Hi-C,
RNAseq,
Mass-spec
evidences		 Cancer
Breakpoint,
PubMed(s)
Name(s)1,
transcript		 Start1..End1
Ident1% 		Strand1
Chrom1 		Name(s)2,
transcript		 Start2..End2
Ident2% 		Strand2
Chrom2
1234,5,67,1989,10,1112,2513,14,15321617
1
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: Z46376 FASTA
UniProtKB: P52789 Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) (Muscle form hexokinase)
Fusion Gene(s): HK2
Head Gene (1) Alignment: FAM50A | OMIM: 300453 Tail Gene (2) Alignment: HK2 | OMIM: 601125 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
9130X-154445689154450648131protein-coding30992+7483415774891986181protein-coding 5292 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Hexokinase_1 (PF00349, IPR022672) 197 857 1055 1.6e-78 249.300 Hexokinase
Hexokinase_2 (PF03727, IPR022673) 239 1061 1295 3.5e-90 287.700 Hexokinase
Updated: 2019-02-21
Owner: ChiTaRS
NM_004699.3		1..1069
100.0%		-
X
NM_000189.4		1067..5289
100.0%		+
2		1
0
0		exon-exon
2
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: BP283909 FASTA
Head Gene (1) Alignment: HK2 | OMIM: 601125 Tail Gene (2) Alignment: HK2P1 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
30992+748340747483464211protein-coding642546X-805745348057503811pseudo 583 hg38
Updated: 2019-03-30
Owner: ChiTaRS
XM_005264280.2		1..570
99.5%		+
2		 HK2P1 77..583
95.9%		-
X		0
58712
5108		exon-exon

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