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Rank: Junction Consistence: Hi-C Sense-ANTIsense

Mass-spec hits Read-through chimeras Breakpoints RNAseq evidence
UniProtKB hits
Organisms
Homo Sapiens Mus musculus D.Melanogaster
Rattus Norvegicus Bos Taurus Danio Rerio
Saccharomyces Cerevisiae Sus ScrofaAll organisms

Result for the search of Gene Name/NCBI ID(s): 'FRYL'

Total of fusion sequences: 23 (from 10,657,267 parsed EST/mRNAs. Last update: 2020-11-05 10:39:19)

Organism Fusion:
Graphical View,
Annotation,
PPI network 		Head Gene (1) Tail Gene (2) Rank,
Deviation:
Eloc(x)
Sloc(y) 		Fusion type RNA Hi-C,
RNAseq,
Mass-spec
evidences		 Cancer
Breakpoint,
PubMed(s)
Name(s)1,
transcript		 Start1..End1
Ident1% 		Strand1
Chrom1 		Name(s)2,
transcript		 Start2..End2
Ident2% 		Strand2
Chrom2
1234,5,67,1989,10,1112,2513,14,15321617
1
Homo Sapiens		SplGraphs

ANNOTATION OF CHIMERA FUSION

GenBank ID: DQ299936 FASTA
Head Gene (1) Alignment: FRYL Tail Gene (2) Alignment: KMT2A | OMIM: 159555 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
2855274-4853115648531345151oncogene,
protein-coding		429711+118488612118489863261oncogene,
protein-coding		 409 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
MOR2-PAG1_N (PF14222, IPR025614) 544 117 649 2.1e-176 574.100 Cell morphogenesis N-terminal
MOR2-PAG1_mid (PF14228, IPR029473) 1114 683 891 0.00015 5.600 Cell morphogenesis central region
MOR2-PAG1_C (PF14225, IPR025481) 253 2001 2254 1.3e-78 250.400 Cell morphogenesis C-terminal
PI3K_P85_iSH2 (PF16454, IPR032498) 161 2783 2913 0.0011 4.800 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
Updated: 2019-02-21
Owner: ChiTaRS
XM_024453990.1		1..190
100.0%		-
4
XM_011542829.2		189..409
100.0%		+
11		0
1155
1299		exon-exonBREAKPOINTs
2
Homo Sapiens		SplGraphs

ANNOTATION OF CHIMERA FUSION

GenBank ID: DQ299937 FASTA
Head Gene (1) Alignment: KMT2A | OMIM: 159555 Tail Gene (2) Alignment: FRYL Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
429711+118484212118484314101oncogene,
protein-coding		2855274-4852761648528338551oncogene,
protein-coding		 695 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Secretin_N_2 (PF07655, IPR011514) 95 61 109 0.021 1.700 Secretin N-terminal domain
YL1 (PF05764, IPR008895) 242 80 229 0.014 1.700 YL1 nuclear protein
AT_hook (PF02178, IPR017956, SM00384) 13 219 227 0.0014 5.200 AT hook motif
Ribosomal_60s (PF00428, IPR001813) 88 366 420 0.0081 3.100 60s Acidic ribosomal protein
Vfa1 (PF08432, IPR013640) 181 429 571 0.00032 7.200 AAA-ATPase Vps4-associated protein 1
DUF3915 (PF13054, IPR025026) 123 856 909 0.00011 8.400 Protein of unknown function (DUF3915)
SR-25 (PF10500, IPR019532) 227 979 1082 0.0026 3.500 Nuclear RNA-splicing-associated protein
zf-CXXC (PF02008, IPR002857) 48 1147 1194 1.2e-17 50.000 CXXC zinc finger domain
DUF755 (PF05501, IPR008474) 123 1170 1262 0.017 1.700 Domain of unknown function (DUF755)
Updated: 2019-02-21
Owner: ChiTaRS
XM_011542829.2		1..103
100.0%		+
11
XM_024453990.1		102..695
99.9%		-
4		3
0
0		exon-exonBREAKPOINTs
3
Homo Sapiens		SplGraphs

ANNOTATION OF CHIMERA FUSION

GenBank ID: DQ299938 FASTA
Head Gene (1) Alignment: KMT2A | OMIM: 159555 Tail Gene (2) Alignment: FRYL Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
429711+118484212118484975111oncogene,
protein-coding		2855274-4852761648528338551oncogene,
protein-coding		 492 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Secretin_N_2 (PF07655, IPR011514) 95 61 109 0.02 1.800 Secretin N-terminal domain
YL1 (PF05764, IPR008895) 242 80 229 0.013 1.700 YL1 nuclear protein
AT_hook (PF02178, IPR017956, SM00384) 13 219 227 0.0014 5.200 AT hook motif
Ribosomal_60s (PF00428, IPR001813) 88 366 420 0.0077 3.100 60s Acidic ribosomal protein
Vfa1 (PF08432, IPR013640) 181 429 571 0.00031 7.300 AAA-ATPase Vps4-associated protein 1
DUF3915 (PF13054, IPR025026) 123 856 909 0.00011 8.500 Protein of unknown function (DUF3915)
SR-25 (PF10500, IPR019532) 227 979 1082 0.0024 3.600 Nuclear RNA-splicing-associated protein
zf-CXXC (PF02008, IPR002857) 48 1147 1194 1.2e-17 50.100 CXXC zinc finger domain
DUF755 (PF05501, IPR008474) 123 1170 1262 0.016 1.700 Domain of unknown function (DUF755)
Pheromone (PF08015, IPR012597) 69 1567 1686 0.062 0.700 Fungal mating-type pheromone
Updated: 2019-02-21
Owner: ChiTaRS
XM_011542829.2		1..217
100.0%		+
11
XM_024453990.1		216..492
100.0%		-
4		3
0
0		exon-exonBREAKPOINTs
4
Homo Sapiens		SplGraphs

ANNOTATION OF CHIMERA FUSION

GenBank ID: AK128543 FASTA
UniProtKB: Q6ZR29 cDNA FLJ46702 fis, clone TRACH3014183
Head Gene (1) Alignment: FRYL Tail Gene (2) Alignment: PRH1-PRR4 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
2855274-4851520948564984351oncogene,
protein-coding		10053346412-1084585110847120101ncRNA 4533 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
MOR2-PAG1_mid (PF14228, IPR029473) 1114 1310 1493 2.7e-20 57.700 Cell morphogenesis central region
MOR2-PAG1_C (PF14225, IPR025481) 253 2164 2417 5.8e-79 251.600 Cell morphogenesis C-terminal
Updated: 2019-02-20
Owner: ChiTaRS
XM_024453990.1		1..4364
100.0%		-
4		 PRH1-PRR4
NR_037918.2		4358..4533
99.5%		-
12		1
0
0		exon-exon
5
Homo Sapiens		SplGraphs

ANNOTATION OF CHIMERA FUSION

GenBank ID: CV569065 FASTA
Head Gene (1) Alignment: FRYL Tail Gene (2) Alignment: PRRX1 | OMIM: 167420 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
2855274-4854617248546241231oncogene,
protein-coding		53961+17073775617073829511oncogene,
protein-coding		 610 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
MOR2-PAG1_N (PF14222, IPR025614) 544 117 649 5.7e-177 575.900 Cell morphogenesis N-terminal
MOR2-PAG1_mid (PF14228, IPR029473) 1114 683 889 5.5e-05 7.000 Cell morphogenesis central region
Updated: 2019-02-21
Owner: ChiTaRS
XM_024453990.1		1..70
100.0%		-
4
XM_006711388.3		71..610
100.0%		+
1		1
0
0		exon-exon
6
Homo Sapiens		 ChimerDB

ANNOTATION OF CHIMERA FUSION

GenBank ID: DQ299940 FASTA
Head Gene (1) Alignment: KMT2A | OMIM: 159555 Tail Gene (2) Alignment: FRYL Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
429711+118484212118484314101oncogene,
protein-coding		2855274-4852761548528338551oncogene,
protein-coding		 491 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Secretin_N_2 (PF07655, IPR011514) 95 61 109 0.02 1.800 Secretin N-terminal domain
YL1 (PF05764, IPR008895) 242 80 229 0.013 1.700 YL1 nuclear protein
AT_hook (PF02178, IPR017956, SM00384) 13 219 227 0.0013 5.300 AT hook motif
Ribosomal_60s (PF00428, IPR001813) 88 366 420 0.0076 3.200 60s Acidic ribosomal protein
Vfa1 (PF08432, IPR013640) 181 429 571 0.0003 7.300 AAA-ATPase Vps4-associated protein 1
DUF1777 (PF08648, IPR013957) 171 698 834 0.049 0.000 Protein of unknown function (DUF1777)
DUF3915 (PF13054, IPR025026) 123 856 909 0.00011 8.500 Protein of unknown function (DUF3915)
SR-25 (PF10500, IPR019532) 227 979 1082 0.0024 3.600 Nuclear RNA-splicing-associated protein
zf-CXXC (PF02008, IPR002857) 48 1147 1194 1.1e-17 50.100 CXXC zinc finger domain
DUF755 (PF05501, IPR008474) 123 1170 1262 0.016 1.800 Domain of unknown function (DUF755)
DUF3446 (PF11928, IPR021849) 88 1424 1476 0.057 0.100 Domain of unknown function (DUF3446)
Pheromone (PF08015, IPR012597) 69 1529 1648 0.053 0.900 Fungal mating-type pheromone
Updated: 2019-02-21
Owner: ChiTaRS
XM_011542829.2		1..103
100.0%		+
11
XM_024453990.1		102..379
100.0%		-
4		3
0
0		exon-exonBREAKPOINTs
7
Homo Sapiens		 ChimerDB

ANNOTATION OF CHIMERA FUSION

GenBank ID: DQ299939 FASTA
Head Gene (1) Alignment: KMT2A | OMIM: 159555 Tail Gene (2) Alignment: FRYL Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
429711+118484212118484314101oncogene,
protein-coding		2855274-4852761648528338551oncogene,
protein-coding		 378 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Secretin_N_2 (PF07655, IPR011514) 95 61 109 0.02 1.800 Secretin N-terminal domain
YL1 (PF05764, IPR008895) 242 80 229 0.013 1.700 YL1 nuclear protein
AT_hook (PF02178, IPR017956, SM00384) 13 219 227 0.0013 5.300 AT hook motif
Ribosomal_60s (PF00428, IPR001813) 88 366 420 0.0076 3.200 60s Acidic ribosomal protein
Vfa1 (PF08432, IPR013640) 181 429 571 0.0003 7.300 AAA-ATPase Vps4-associated protein 1
DUF1777 (PF08648, IPR013957) 171 698 834 0.049 0.000 Protein of unknown function (DUF1777)
DUF3915 (PF13054, IPR025026) 123 856 909 0.00011 8.500 Protein of unknown function (DUF3915)
SR-25 (PF10500, IPR019532) 227 979 1082 0.0024 3.600 Nuclear RNA-splicing-associated protein
zf-CXXC (PF02008, IPR002857) 48 1147 1194 1.1e-17 50.100 CXXC zinc finger domain
DUF755 (PF05501, IPR008474) 123 1170 1262 0.016 1.800 Domain of unknown function (DUF755)
DUF3446 (PF11928, IPR021849) 88 1424 1476 0.057 0.100 Domain of unknown function (DUF3446)
Pheromone (PF08015, IPR012597) 69 1529 1648 0.053 0.900 Fungal mating-type pheromone
Updated: 2019-02-21
Owner: ChiTaRS
XM_011542829.2		1..103
100.0%		+
11
XM_024453990.1		102..378
100.0%		-
4		3
0
0		exon-exonBREAKPOINTs
8
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: DQ299934 FASTA
Head Gene (1) Alignment: FRYL Tail Gene (2) Alignment: KMT2A | OMIM: 159555 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
2855274-485297664853019000oncogene,
protein-coding		429711+11848731311848982520oncogene,
protein-coding		 2992 hg38
Updated: 2019-03-03
Owner: ChiTaRS
XM_024453990.1		56..480
99.6%		-
4
XM_011542830.2		478..2992
99.7%		+
11		3
456
171		intron-intronBREAKPOINTs
9
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: DQ299935 FASTA
Head Gene (1) Alignment: KMT2A | OMIM: 159555 Tail Gene (2) Alignment: FRYL Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
429711+118487142118487304110oncogene,
protein-coding		2855274-4852947648529734520oncogene,
protein-coding		 420 hg38
Updated: 2019-02-21
Owner: ChiTaRS
XM_011542829.2		1..163
100.0%		+
11
XM_024453990.1		162..420
100.0%		-
4		3
456
171		intron-intronBREAKPOINTs
10
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AL137546 FASTA
UniProtKB: O94915 Protein furry homolog-like (ALL1-fused gene from chromosome 4p12 protein)
Fusion Gene(s): FRYL AF4P12 KIAA0826
Head Gene (1) Alignment: FRYL Tail Gene (2) Alignment: CNOT2 | OMIM: 604909 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
2855274-484984684850165931oncogene,
protein-coding		484812-7025735370257374180protein-coding 1457 hg38
Updated: 2019-01-30
Owner: ChiTaRS
XM_024453990.1		1..1441
100.0%		-
4
XM_017019352.1		1436..1457
100.0%		-
12		1
0
0		exon-intron

T O P