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Rank: Junction Consistence: Hi-C Sense-ANTIsense

Mass-spec hits Read-through chimeras Breakpoints RNAseq evidence
UniProtKB hits
Organisms
Homo Sapiens Mus musculus D.Melanogaster
Rattus Norvegicus Bos Taurus Danio Rerio
Saccharomyces Cerevisiae Sus ScrofaAll organisms

Result for the search of Gene Name/NCBI ID(s): 'CTSL'

Total of fusion sequences: 11 (from 10,657,267 parsed EST/mRNAs. Last update: 2020-11-05 10:39:19)

Organism Fusion:
Graphical View,
Annotation,
PPI network 		Head Gene (1) Tail Gene (2) Rank,
Deviation:
Eloc(x)
Sloc(y) 		Fusion type RNA Hi-C,
RNAseq,
Mass-spec
evidences		 Cancer
Breakpoint,
PubMed(s)
Name(s)1,
transcript		 Start1..End1
Ident1% 		Strand1
Chrom1 		Name(s)2,
transcript		 Start2..End2
Ident2% 		Strand2
Chrom2
1234,5,67,1989,10,1112,2513,14,15321617
1
Homo Sapiens		SplGraphs

ANNOTATION OF CHIMERA FUSION

GenBank ID: BQ670981 FASTA
Head Gene (1) Alignment: CTSL | OMIM: 116880 Tail Gene (2) Alignment: SENP3-EIF4A1 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
15149+877286598773113191oncogene,
protein-coding		10053395517+7578558757884511ncRNA 847 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Inhibitor_I29 (PF08246, IPR013201, SM00848) 58 29 88 1.4e-15 43.800 Cathepsin propeptide inhibitor domain (I29)
Peptidase_C1 (PF00112, IPR000668, SM00645) 219 114 332 2.2e-89 285.400 Papain family cysteine protease
Updated: 2019-02-21
Owner: ChiTaRS
XM_005251716.4		1..556
100.0%		+
9		 SENP3-EIF4A1
A0A087X0R7
NR_037926.1		551..840
98.3%		+
17		1
0
0		exon-exon
2
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: CB242452 FASTA
Head Gene (1) Alignment: CTSL | OMIM: 116880 Tail Gene (2) Alignment: CTSL | OMIM: 116880 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
15149-877312358773139391oncogene,
protein-coding		15149+877311628773123811oncogene,
protein-coding		 255 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Inhibitor_I29 (PF08246, IPR013201, SM00848) 58 325 384 2.9e-15 42.800 Cathepsin propeptide inhibitor domain (I29)
Peptidase_C1 (PF00112, IPR000668, SM00645) 219 410 628 6.8e-89 283.800 Papain family cysteine protease
Updated: 2019-02-02
Owner: ChiTaRS
XM_005251716.4		18..176
100.0%		-
9
XM_005251716.4		170..246
100.0%		+
9		2
4
80		exon-exonHS111
3
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: BC012612 FASTA
UniProtKB: P07711 Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain]
Fusion Gene(s): CTSL CTSL1
Head Gene (1) Alignment: CTSL | OMIM: 116880 Tail Gene (2) Alignment: ZFR2 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
15149+877262158773138991oncogene,
protein-coding		2321719+3845469384549400protein-coding 1517 hg38
Updated: 2019-04-13
Owner: ChiTaRS
XM_005251716.4		5..1482
100.0%		+
9
NM_015174.1		1474..1499
100.0%		+
19		1
0
0		exon-intron
4
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: BF994660 FASTA
Head Gene (1) Alignment: CTSL | OMIM: 116880 Tail Gene (2) Alignment: CTSL | OMIM: 116880 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
15149-877283168772839351oncogene,
protein-coding		15149+877286358772869341oncogene,
protein-coding		 121 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Inhibitor_I29 (PF08246, IPR013201, SM00848) 58 29 88 8e-16 44.600 Cathepsin propeptide inhibitor domain (I29)
Peptidase_C1 (PF00112, IPR000668, SM00645) 219 114 334 8.4e-71 224.600 Papain family cysteine protease
Updated: 2019-02-02
Owner: ChiTaRS
XM_005251716.4		3..77
98.7%		-
9
XM_005251716.4		63..121
100.0%		+
9		0
2849
2520		exon-exon
5
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: BQ774810 FASTA
Head Gene (1) Alignment: CTSL | OMIM: 116880 Tail Gene (2) Alignment: CTSL | OMIM: 116880 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
15149-877311558773139391oncogene,
protein-coding		15149+877296818773124231oncogene,
protein-coding		 667 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Inhibitor_I29 (PF08246, IPR013201, SM00848) 58 325 384 3.3e-15 42.600 Cathepsin propeptide inhibitor domain (I29)
Peptidase_C1 (PF00112, IPR000668, SM00645) 219 410 628 8e-89 283.600 Papain family cysteine protease
Updated: 2019-02-02
Owner: ChiTaRS
XM_005251716.4		18..257
98.4%		-
9
XM_005251716.4		253..667
99.8%		+
9		2
4
80		exon-exon
6
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: BE836763 FASTA
Head Gene (1) Alignment: PGM5 | OMIM: 600981 Tail Gene (2) Alignment: CTSL | OMIM: 116880 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
52399-6853070968530772111protein-coding15149-877287138772968041oncogene,
protein-coding		 275 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Peptidase_C1 (PF00112, IPR000668, SM00645) 219 1332 1492 7.7e-57 179.000 Papain family cysteine protease
Updated: 2019-02-20
Owner: ChiTaRS
NM_021965.3		5..68
98.5%		-
9
XM_005251716.4		63..267
100.0%		-
9		1
0
0		exon-exon
7
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: BE836772 FASTA
Head Gene (1) Alignment: PGM5 | OMIM: 600981 Tail Gene (2) Alignment: CTSL | OMIM: 116880 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
52399-6853070968530772111protein-coding15149-877287138772968041oncogene,
protein-coding		 279 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Peptidase_C1 (PF00112, IPR000668, SM00645) 219 1332 1492 7.7e-57 179.000 Papain family cysteine protease
Updated: 2019-02-20
Owner: ChiTaRS
NM_021965.3		9..72
96.9%		-
9
XM_005251716.4		67..271
99.6%		-
9		1
0
0		exon-exon
8
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AA947420 FASTA
Head Gene (1) Alignment: CTSL | OMIM: 116880 Tail Gene (2) Alignment: SUGT1P4-STRA6LP-CCDC180 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
15149-877311788773139391oncogene,
protein-coding		576539-9729709597297207370ncRNA 324 hg38
Updated: 2019-02-20
Owner: ChiTaRS
XM_005251716.4		3..218
100.0%		-
9		 SUGT1P4-STRA6LP-CCDC180
NR_036528.1		212..324
99.2%		-
9		1
0
0		exon-intron
9
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: CB050631 FASTA
Head Gene (1) Alignment: HSF2BP | OMIM: 604554 Tail Gene (2) Alignment: CTSL | OMIM: 116880 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
1107721-435580024355803000protein-coding15149-877311508773139311oncogene,
protein-coding		 274 hg38
Updated: 2019-04-13
Owner: ChiTaRS
XM_017028269.1		11..36
100.0%		-
21
XM_005251716.4		30..274
97.2%		-
9		1
0
0		intron-exon
10
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: CA411570 FASTA
Head Gene (1) Alignment: CTSL | OMIM: 116880 Tail Gene (2) Alignment: FHL1 | OMIM: 300163 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
15149-877313428773139391oncogene,
protein-coding		2273X-13620917613620925120tumor suppressor,
protein-coding		 138 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Inhibitor_I29 (PF08246, IPR013201, SM00848) 58 325 384 3.6e-15 42.500 Cathepsin propeptide inhibitor domain (I29)
Peptidase_C1 (PF00112, IPR000668, SM00645) 219 410 628 9.1e-89 283.400 Papain family cysteine protease
Updated: 2019-02-21
Owner: ChiTaRS
XM_005251716.4		18..69
100.0%		-
9
XM_024452353.1		63..138
97.4%		-
X		1
0
0		exon-intron

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