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Rank: Junction Consistence: Hi-C Sense-ANTIsense

Mass-spec hits Read-through chimeras Breakpoints RNAseq evidence
UniProtKB hits
Organisms
Homo Sapiens Mus musculus D.Melanogaster
Rattus Norvegicus Bos Taurus Danio Rerio
Saccharomyces Cerevisiae Sus ScrofaAll organisms

Result for the search of Gene Name/NCBI ID(s): '4297,4300'

Total of fusion sequences: 22 (from 1,393,046 parsed EST/mRNAs. Last update 2019-09-04)

Organism Fusion:
Graphical View,
Annotation,
PPI network 		Head Gene (1) Tail Gene (2) Rank,
Deviation:
Eloc(x)
Sloc(y) 		Fusion type RNA Hi-C,
RNAseq,
Mass-spec
evidences		 Cancer
Breakpoint,
PubMed(s)
Name(s)1,
transcript		 Start1..End1
Ident1% 		Strand1
Chrom1 		Name(s)2,
transcript		 Start2..End2
Ident2% 		Strand2
Chrom2
1234,5,67,1989,10,1112,2513,14,15321617
1
Homo Sapiens		 ChimerDB

ANNOTATION OF CHIMERA FUSION

GenBank ID: EF406122 FASTA
Head Gene (1) Alignment: KMT2A | OMIM: 159555 Tail Gene (2) Alignment: MLLT3 | OMIM: 159558 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
429711+11848199611848209481oncogene43009-203634832036360971oncogene 220 hg38
Updated: 2019-02-02
Owner: ChiTaRS
XM_011542829.2		1..99
100.0%		+
11
NM_004529.3		94..220
100.0%		-
9		0
3578
757		exon-exon1RNA-seq
BREAKPOINTs
2
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: EU669177 FASTA
Head Gene (1) Alignment: KMT2A | OMIM: 159555 Tail Gene (2) Alignment: MLLT3 | OMIM: 159558 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
429711+11848244811848290790oncogene43009-206220822062255510oncogene 928 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
AT_hook (PF02178, IPR017956, SM00384) 13 173 183 0.036 0.800 AT hook motif
Ribosomal_60s (PF00428, IPR001813) 88 366 420 0.008 3.100 60s Acidic ribosomal protein
Apt1 (PF10351, IPR019443) 478 400 609 0.0022 2.900 Golgi-body localisation protein domain
DUF3915 (PF13054, IPR025026) 123 856 909 0.00011 8.400 Protein of unknown function (DUF3915)
zf-CXXC (PF02008, IPR002857) 48 1147 1194 1.2e-17 50.000 CXXC zinc finger domain
Updated: 2019-02-17
Owner: ChiTaRS
XM_011542829.2		1..457
100.0%		+
11
NM_004529.3		455..928
96.3%		-
9		0
65535
305		intron-intron1RNA-seq
BREAKPOINTs
3
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AY282398 FASTA
Head Gene (1) Alignment: KMT2A | OMIM: 159555 Tail Gene (2) Alignment: MLLT3 | OMIM: 159558 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
429711+118488217118488420110oncogene43009-203730912037330550oncogene 409 hg38
Updated: 2019-02-20
Owner: ChiTaRS
XM_011542829.2		1..204
100.0%		+
11
NM_004529.3		194..409
98.6%		-
9		0
40021
12		intron-intron1RNA-seq
BREAKPOINTs
4
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AM050804 FASTA
Head Gene (1) Alignment: KMT2A | OMIM: 159555 Tail Gene (2) Alignment: MLLT3 | OMIM: 159558 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
429711+118487561118487875110oncogene43009-203775332037793650oncogene 680 hg38
Updated: 2019-02-20
Owner: ChiTaRS
XM_011542829.2		1..315
100.0%		+
11
NM_004529.3		309..680
100.0%		-
9		0
14835
140		intron-intron1RNA-seq
BREAKPOINTs
5
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: S82034 FASTA
Head Gene (1) Alignment: KMT2A | OMIM: 159555 Tail Gene (2) Alignment: MLLT3 | OMIM: 159558 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
429711+118484948118484976111oncogene43009-204143942041442751oncogene 60 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
SelK_SelG (PF10961, IPR024491) 86 3 50 0.074 0.000 Selenoprotein SelK_SelG
Filament_head (PF04732, IPR006821) 87 53 131 0.0073 3.500 Intermediate filament head (DNA binding) region
YL1 (PF05764, IPR008895) 242 80 228 0.011 1.900 YL1 nuclear protein
AT_hook (PF02178, IPR017956, SM00384) 13 219 227 0.0012 5.400 AT hook motif
Ribosomal_60s (PF00428, IPR001813) 88 366 420 0.0066 3.300 60s Acidic ribosomal protein
Vfa1 (PF08432, IPR013640) 181 429 571 0.00026 7.500 AAA-ATPase Vps4-associated protein 1
DUF3915 (PF13054, IPR025026) 123 856 909 9.2e-05 8.700 Protein of unknown function (DUF3915)
SR-25 (PF10500, IPR019532) 227 979 1082 0.002 3.800 Nuclear RNA-splicing-associated protein
zf-CXXC (PF02008, IPR002857) 48 1147 1194 9.9e-18 50.300 CXXC zinc finger domain
DUF755 (PF05501, IPR008474) 123 1170 1262 0.014 2.000 Domain of unknown function (DUF755)
SID-1_RNA_chan (PF13965, IPR025958) 607 1382 1542 0.00045 4.800 dsRNA-gated channel SID-1
PA26 (PF04636, IPR006730) 440 1431 1563 0.0078 1.200 PA26 p53-induced protein (sestrin)
DUF3446 (PF11928, IPR021849) 88 1555 1637 0.036 0.700 Domain of unknown function (DUF3446)
PBP1_TM (PF14812, IPR032730) 85 1693 1752 0.00028 7.600 Transmembrane domain of transglycosylase PBP1 at N-terminal
SARAF (PF06682, IPR009567) 328 1721 1805 0.027 0.200 SOCE-associated regulatory factor of calcium homoeostasis
BET (PF17035, IPR027353) 64 1808 1868 1.3e-05 11.600 Bromodomain extra-terminal - transcription regulation
Updated: 2019-01-29
Owner: ChiTaRS
XM_011542829.2		1..29
100.0%		+
11
NM_004529.3		27..60
100.0%		-
9		0
11969
79		exon-exon1RNA-seq
BREAKPOINTs
6
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AY840548 FASTA
Head Gene (1) Alignment: KMT2A | OMIM: 159555 Tail Gene (2) Alignment: MLLT3 | OMIM: 159558 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
429711+118485027118485073110oncogene43009-204022202040245850oncogene 284 hg38
Updated: 2019-02-20
Owner: ChiTaRS
XM_011542829.2		1..47
95.8%		+
11
NM_004529.3		47..284
99.2%		-
9		0
11969
79		intron-intron1RNA-seq
BREAKPOINTs
7
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AY282395 FASTA
Head Gene (1) Alignment: KMT2A | OMIM: 159555 Tail Gene (2) Alignment: MLLT3 | OMIM: 159558 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
429711+118488018118488418110oncogene43009-203989562039906350oncogene 512 hg38
Updated: 2019-02-23
Owner: ChiTaRS
XM_011542829.2		7..406
100.0%		+
11
NM_004529.3		406..512
100.0%		-
9		0
11490
199		intron-intron1RNA-seq
BREAKPOINTs
8
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AY840545 FASTA
Head Gene (1) Alignment: KMT2A | OMIM: 159555 Tail Gene (2) Alignment: MLLT3 | OMIM: 159558 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
429711+118487473118487667110oncogene43009-204033832040355150oncogene 364 hg38
Updated: 2019-02-20
Owner: ChiTaRS
XM_011542829.2		1..195
100.0%		+
11
NM_004529.3		196..364
100.0%		-
9		0
10780
52		intron-intron1RNA-seq
BREAKPOINTs
9
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AY840546 FASTA
Head Gene (1) Alignment: KMT2A | OMIM: 159555 Tail Gene (2) Alignment: MLLT3 | OMIM: 159558 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
429711+118487421118487462110oncogene43009-203923652039277150oncogene 461 hg38
Updated: 2019-02-22
Owner: ChiTaRS
XM_011542829.2		16..56
97.6%		+
11
NM_004529.3		55..460
100.0%		-
9		0
10780
52		intron-intron1RNA-seq
BREAKPOINTs
10
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AY387663 FASTA
Head Gene (1) Alignment: KMT2A | OMIM: 159555 Tail Gene (2) Alignment: MLLT3 | OMIM: 159558 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
429711+11848822911848841800oncogene43009-204130602041332600oncogene 452 hg38
Updated: 2019-09-04
Owner: ChiTaRS
XM_011542830.2		1..190
100.0%		+
11
NM_001286691.1		186..452
100.0%		-
9		0
2773
12		intron-intron1RNA-seq
BREAKPOINTs

T o p