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Rank: Junction Consistence: Hi-C Sense-ANTIsense

Mass-spec hits Read-through chimeras Breakpoints RNAseq evidence
UniProtKB hits
Organisms
Homo Sapiens Mus musculus D.Melanogaster
Rattus Norvegicus Bos Taurus Danio Rerio
Saccharomyces Cerevisiae Sus ScrofaAll organisms

Result for the search of Gene Name/NCBI ID(s): '3799,5979'

Total of fusion sequences: 15 (from 6,491,097 parsed EST/mRNAs. Last update: 2020-08-30 12:24:27)

Organism Fusion:
Graphical View,
Annotation,
PPI network 		Head Gene (1) Tail Gene (2) Rank,
Deviation:
Eloc(x)
Sloc(y) 		Fusion type RNA Hi-C,
RNAseq,
Mass-spec
evidences		 Cancer
Breakpoint,
PubMed(s)
Name(s)1,
transcript		 Start1..End1
Ident1% 		Strand1
Chrom1 		Name(s)2,
transcript		 Start2..End2
Ident2% 		Strand2
Chrom2
1234,5,67,1989,10,1112,2513,14,15321617
1
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AB795249 FASTA
UniProtKB: M1VPF7 Kinesin-like protein
Fusion Gene(s): KIF5B-RET(NM_020630)_K15;R12
Head Gene (1) Alignment: KIF5B | OMIM: 602809 Tail Gene (2) Alignment: RET | OMIM: 164761 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
379910-3202842732056182261protein-coding597910+431165824312684491oncogene,
protein-coding		 3107 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Kinesin (PF00225, IPR001752, SM00129) 333 83 394 2.4e-116 374.300 Kinesin motor domain
Mrr_N (PF14338, IPR025745) 87 387 438 4.3e-05 9.900 Mrr N-terminal domain
ERM (PF00769, IPR011259) 243 483 664 1.7e-06 14.100 Ezrin/radixin/moesin family
Pkinase_Tyr (PF07714, IPR001245) 260 656 937 3e-105 337.200 Protein tyrosine kinase
Updated: 2019-02-20
Owner: ChiTaRS
NM_004521.2		1..1935
100.0%		-
10
NM_020975.5		1933..3107
100.0%		+
10		3
0
0		exon-exonBREAKPOINTs
2
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AB795257 FASTA
UniProtKB: M1VE91 KIF5B-RET(NM_020630)_K24R11 fusion protein
Fusion Gene(s): KIF5B-RET(NM_020630)_K24;R11
Head Gene (1) Alignment: KIF5B | OMIM: 602809 Tail Gene (2) Alignment: RET | OMIM: 164761 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
379910-3201714332056182261protein-coding597910+4311447943126844101oncogene,
protein-coding		 4400 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Kinesin (PF00225, IPR001752, SM00129) 333 83 394 4.2e-116 373.500 Kinesin motor domain
PRKG1_interact (PF15898, IPR031775) 102 408 471 0.00014 9.100 cGMP-dependent protein kinase interacting domain
DUF3584 (PF12128, IPR021979) 1200 471 719 5.5e-07 13.500 Protein of unknown function (DUF3584)
Reo_sigmaC (PF04582, IPR007662) 326 661 815 5.7e-06 12.000 Reovirus sigma C capsid protein
HAUS-augmin3 (PF14932, IPR032733) 258 799 885 3.6e-05 9.500 HAUS augmin-like complex subunit 3
CENP-F_leu_zip (PF10473, IPR019513) 140 892 982 6.6e-06 12.400 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
DUF2721 (PF11026, IPR021279) 129 929 1022 8.7e-05 8.700 Protein of unknown function (DUF2721)
DUF106 (PF01956, IPR002809) 170 994 1044 0.00069 5.600 Integral membrane protein DUF106
Pkinase_Tyr (PF07714, IPR001245) 260 1087 1368 5.3e-105 336.400 Protein tyrosine kinase
Updated: 2019-02-20
Owner: ChiTaRS
NM_004521.2		1..2970
100.0%		-
10
NM_020975.5		2970..4400
99.9%		+
10		0
0
2103		exon-exonBREAKPOINTs
3
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AB795256 FASTA
UniProtKB: M1VKJ2 KIF5B-RET(NM_020975)_K23R12 fusion protein
Fusion Gene(s): KIF5B-RET(NM_020975)_K23;R12
Head Gene (1) Alignment: KIF5B | OMIM: 602809 Tail Gene (2) Alignment: RET | OMIM: 164761 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
379910-3201805132056182261protein-coding597910+431165824312831491oncogene,
protein-coding		 4007 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Kinesin (PF00225, IPR001752, SM00129) 333 83 394 3.4e-116 373.800 Kinesin motor domain
PRKG1_interact (PF15898, IPR031775) 102 408 471 0.00012 9.300 cGMP-dependent protein kinase interacting domain
DUF3584 (PF12128, IPR021979) 1200 472 718 7.4e-07 13.000 Protein of unknown function (DUF3584)
ATG16 (PF08614, IPR013923) 203 654 765 8.9e-06 12.100 Autophagy protein 16 (ATG16)
Reo_sigmaC (PF04582, IPR007662) 326 664 814 5.8e-06 12.000 Reovirus sigma C capsid protein
HAUS-augmin3 (PF14932, IPR032733) 258 797 882 2.6e-05 10.000 HAUS augmin-like complex subunit 3
DUF1690 (PF07956, IPR012471) 139 831 931 0.00032 7.400 Protein of Unknown function (DUF1690)
Pkinase_Tyr (PF07714, IPR001245) 260 929 1210 4.3e-105 336.700 Protein tyrosine kinase
Updated: 2019-02-20
Owner: ChiTaRS
NM_004521.2		1..2754
100.0%		-
10
NM_020975.5		2752..4007
100.0%		+
10		3
0
0		exon-exonBREAKPOINTs
4
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AB795255 FASTA
UniProtKB: M1VRN1 KIF5B-RET(NM_020630)_K23R12 fusion protein
Fusion Gene(s): KIF5B-RET(NM_020630)_K23;R12
Head Gene (1) Alignment: KIF5B | OMIM: 602809 Tail Gene (2) Alignment: RET | OMIM: 164761 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
379910-3201805132056182261protein-coding597910+431165824312684491oncogene,
protein-coding		 3926 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Kinesin (PF00225, IPR001752, SM00129) 333 83 394 3.5e-116 373.800 Kinesin motor domain
PRKG1_interact (PF15898, IPR031775) 102 408 471 0.00012 9.300 cGMP-dependent protein kinase interacting domain
DUF3584 (PF12128, IPR021979) 1200 472 718 7.6e-07 13.000 Protein of unknown function (DUF3584)
ATG16 (PF08614, IPR013923) 203 654 765 9.1e-06 12.100 Autophagy protein 16 (ATG16)
Reo_sigmaC (PF04582, IPR007662) 326 664 814 5.6e-06 12.000 Reovirus sigma C capsid protein
HAUS-augmin3 (PF14932, IPR032733) 258 799 882 2.1e-05 10.300 HAUS augmin-like complex subunit 3
DUF1690 (PF07956, IPR012471) 139 831 931 0.00032 7.300 Protein of Unknown function (DUF1690)
Pkinase_Tyr (PF07714, IPR001245) 260 929 1210 4.4e-105 336.700 Protein tyrosine kinase
Updated: 2019-02-20
Owner: ChiTaRS
NM_004521.2		1..2754
100.0%		-
10
NM_020975.5		2752..3926
99.9%		+
10		3
0
0		exon-exonBREAKPOINTs
5
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AB795254 FASTA
UniProtKB: M1VPF9 KIF5B-RET(NM_020975)_K22R12 fusion protein
Fusion Gene(s): KIF5B-RET(NM_020975)_K22;R12
Head Gene (1) Alignment: KIF5B | OMIM: 602809 Tail Gene (2) Alignment: RET | OMIM: 164761 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
379910-3201831532056182261protein-coding597910+431165824312831491oncogene,
protein-coding		 3902 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Kinesin (PF00225, IPR001752, SM00129) 333 83 394 3.3e-116 373.900 Kinesin motor domain
PRKG1_interact (PF15898, IPR031775) 102 408 471 0.00012 9.300 cGMP-dependent protein kinase interacting domain
DUF3584 (PF12128, IPR021979) 1200 473 720 6.1e-07 13.300 Protein of unknown function (DUF3584)
ATG16 (PF08614, IPR013923) 203 653 765 1.1e-05 11.900 Autophagy protein 16 (ATG16)
Reo_sigmaC (PF04582, IPR007662) 326 663 834 7.2e-06 11.600 Reovirus sigma C capsid protein
HAUS-augmin3 (PF14932, IPR032733) 258 798 876 2.3e-05 10.100 HAUS augmin-like complex subunit 3
TolA_bind_tri (PF16331, IPR032519) 76 815 886 0.0077 2.700 TolA binding protein trimerisation
Pkinase_Tyr (PF07714, IPR001245) 260 894 1175 4.1e-105 336.800 Protein tyrosine kinase
Updated: 2019-02-20
Owner: ChiTaRS
NM_004521.2		1..2649
100.0%		-
10
NM_020975.5		2647..3902
100.0%		+
10		3
0
0		exon-exonBREAKPOINTs
6
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AB795253 FASTA
UniProtKB: M1V490 KIF5B-RET(NM_020630)_K22R12 fusion protein
Fusion Gene(s): KIF5B-RET(NM_020630)_K22;R12
Head Gene (1) Alignment: KIF5B | OMIM: 602809 Tail Gene (2) Alignment: RET | OMIM: 164761 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
379910-3201831532056182261protein-coding597910+431165824312684491oncogene,
protein-coding		 3821 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Kinesin (PF00225, IPR001752, SM00129) 333 83 394 3.4e-116 373.800 Kinesin motor domain
PRKG1_interact (PF15898, IPR031775) 102 408 471 0.00012 9.300 cGMP-dependent protein kinase interacting domain
DUF3584 (PF12128, IPR021979) 1200 473 720 6.7e-07 13.200 Protein of unknown function (DUF3584)
ATG16 (PF08614, IPR013923) 203 653 765 1.1e-05 11.800 Autophagy protein 16 (ATG16)
Reo_sigmaC (PF04582, IPR007662) 326 663 834 7.6e-06 11.600 Reovirus sigma C capsid protein
HAUS-augmin3 (PF14932, IPR032733) 258 798 876 2.5e-05 10.000 HAUS augmin-like complex subunit 3
DUF641 (PF04859, IPR006943) 127 848 934 0.0084 2.700 Plant protein of unknown function (DUF641)
Pkinase_Tyr (PF07714, IPR001245) 260 894 1175 4.3e-105 336.800 Protein tyrosine kinase
Updated: 2019-02-20
Owner: ChiTaRS
NM_004521.2		1..2649
100.0%		-
10
NM_020975.5		2647..3821
100.0%		+
10		3
0
0		exon-exonBREAKPOINTs
7
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AB795252 FASTA
UniProtKB: M1VE89 KIF5B-RET(NM_020975)_K16R12 fusion protein
Fusion Gene(s): KIF5B-RET(NM_020975)_K16;R12
Head Gene (1) Alignment: KIF5B | OMIM: 602809 Tail Gene (2) Alignment: RET | OMIM: 164761 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
379910-3202284732056182261protein-coding597910+431165844312831491oncogene,
protein-coding		 3377 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Kinesin (PF00225, IPR001752, SM00129) 333 83 394 2.5e-116 374.300 Kinesin motor domain
Mrr_N (PF14338, IPR025745) 87 387 438 4.5e-05 9.900 Mrr N-terminal domain
DUF724 (PF05266, IPR007930) 188 483 571 5.8e-06 12.400 Protein of unknown function (DUF724)
Syntaxin-6_N (PF09177, IPR015260) 99 551 674 1.9e-05 11.500 Syntaxin 6, N-terminal
ATG16 (PF08614, IPR013923) 203 652 713 0.0003 7.200 Autophagy protein 16 (ATG16)
Pkinase_Tyr (PF07714, IPR001245) 260 719 1000 3.2e-105 337.200 Protein tyrosine kinase
Updated: 2019-02-20
Owner: ChiTaRS
NM_004521.2		1..2124
100.0%		-
10
NM_020975.5		2124..3377
99.9%		+
10		3
0
0		exon-exonBREAKPOINTs
8
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AB795251 FASTA
UniProtKB: M1VKI9 Kinesin-like protein
Fusion Gene(s): KIF5B-RET(NM_020630)_K16;R12
Head Gene (1) Alignment: KIF5B | OMIM: 602809 Tail Gene (2) Alignment: RET | OMIM: 164761 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
379910-3202284732056182261protein-coding597910+431165844312684491oncogene,
protein-coding		 3296 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Kinesin (PF00225, IPR001752, SM00129) 333 83 394 2.6e-116 374.200 Kinesin motor domain
Mrr_N (PF14338, IPR025745) 87 387 438 4.6e-05 9.900 Mrr N-terminal domain
DUF724 (PF05266, IPR007930) 188 483 571 6e-06 12.300 Protein of unknown function (DUF724)
Syntaxin-6_N (PF09177, IPR015260) 99 550 674 2.1e-05 11.300 Syntaxin 6, N-terminal
ATG16 (PF08614, IPR013923) 203 652 713 0.0003 7.100 Autophagy protein 16 (ATG16)
Pkinase_Tyr (PF07714, IPR001245) 260 719 1000 3.3e-105 337.100 Protein tyrosine kinase
Updated: 2019-02-20
Owner: ChiTaRS
NM_004521.2		1..2124
100.0%		-
10
NM_020975.5		2124..3296
99.8%		+
10		3
0
0		exon-exonBREAKPOINTs
9
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: AB795250 FASTA
UniProtKB: M1VRN0 Kinesin-like protein
Fusion Gene(s): KIF5B-RET(NM_020975)_K15;R12
Head Gene (1) Alignment: KIF5B | OMIM: 602809 Tail Gene (2) Alignment: RET | OMIM: 164761 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
379910-3202842732056182261protein-coding597910+431165824312831491oncogene,
protein-coding		 3188 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Kinesin (PF00225, IPR001752, SM00129) 333 83 394 2.3e-116 374.400 Kinesin motor domain
Mrr_N (PF14338, IPR025745) 87 387 438 4.2e-05 10.000 Mrr N-terminal domain
ERM (PF00769, IPR011259) 243 483 664 1.6e-06 14.200 Ezrin/radixin/moesin family
Pkinase_Tyr (PF07714, IPR001245) 260 656 937 2.9e-105 337.300 Protein tyrosine kinase
Updated: 2019-02-20
Owner: ChiTaRS
NM_004521.2		1..1935
100.0%		-
10
NM_020975.5		1933..3188
100.0%		+
10		3
0
0		exon-exonBREAKPOINTs
10
Homo Sapiens

ANNOTATION OF CHIMERA FUSION

GenBank ID: HW088352 FASTA
Head Gene (1) Alignment: KIF5B | OMIM: 602809 Tail Gene (2) Alignment: RET | OMIM: 164761 Qsize UCSC
Version
Location:
 exons highlight1 Location:
 exons highlight2
Entrez
GeneID1		 chromo-
some1		 strand1 start_loc1 end_loc1 total1 overlap1 Entrez
GeneID2		 chromo-
some2		 strand2 start_loc2 end_loc2 total2 overlap2
1819720212223-24251226272829-3031
379910-3201714332056443261protein-coding597910+4311209843130351131oncogene,
protein-coding		 7148 hg38

Domains of the full fusion Envelope E-value Score Description
name (Pfam, InterPro, SMART) length from to
Kinesin (PF00225, IPR001752, SM00129) 333 170 481 8.3e-116 372.600 Kinesin motor domain
PRKG1_interact (PF15898, IPR031775) 102 495 558 0.00023 8.400 cGMP-dependent protein kinase interacting domain
DUF3584 (PF12128, IPR021979) 1200 560 807 1.8e-06 11.800 Protein of unknown function (DUF3584)
ATG16 (PF08614, IPR013923) 203 741 853 1.7e-05 11.200 Autophagy protein 16 (ATG16)
Reo_sigmaC (PF04582, IPR007662) 326 750 904 1.1e-05 11.100 Reovirus sigma C capsid protein
HAUS-augmin3 (PF14932, IPR032733) 258 882 969 8.1e-05 8.300 HAUS augmin-like complex subunit 3
CENP-F_leu_zip (PF10473, IPR019513) 140 979 1071 5.4e-06 12.700 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
DUF106 (PF01956, IPR002809) 170 1200 1250 0.0011 4.900 Integral membrane protein DUF106
Pkinase_Tyr (PF07714, IPR001245) 260 1293 1574 1e-104 335.500 Protein tyrosine kinase
Updated: 2019-02-21
Owner: ChiTaRS
NM_004521.2		1..3231
100.0%		-
10
NM_020975.5		3231..7136
100.0%		+
10		0
261
2381		exon-exonBREAKPOINTs

T O P