Analysis of Chromosomal Breakpoints

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Cancer Type:




 

Drug Therapy:

Disease:


Set a mask for the chromosome/locus combinations

Chromosome Breakpoints info

Result of search 'TPM3 & ROS1'

Total Breakpoints: 2

PubMed
reference(s) 		Type of Aberration ChiPPI
network		 UniProtKB
fusion		 Gene symbol1 Gene symbol2 RNAseq,
Mass-spec
evidence		 Cancer type &
Drug Therapy (DT)		 Description of Diseases
1 2 3456789
more info
1		 t(1;6)(q21;q22)
 

Drug Therapy

Cancer Type: CESC
Cancer descriptoin: Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma

Drug Therapy

Cancer Type: COADREAD
Cancer descriptoin: Colon Adenocarcinoma and Rectum Adenocarcinoma
Medical Subject Headings (MeSH): D015179
Diseases Database: 2975
Cancer target Gene target Drug therapy Evidence level Effect Link (Pubmed)
COADREAD ROS1 Crizotinib 27397505
COADREAD ROS1 Entrectinib 28183697

Drug Therapy

Cancer Type: LUAD
Cancer descriptoin: Lung Adenocarcinoma
Medical Subject Headings (MeSH): D000077192
Cancer target Gene target Drug therapy Evidence level Effect Link (Pubmed)
LUAD ROS1 Crizotinib Clinical TrialsSensitive25264305
LUAD ROS1 Crizotinib 27397505

Drug Therapy

Cancer Type: OV
Cancer descriptoin: Ovarian Serous Cystadenocarcinoma
Medical Subject Headings (MeSH): D010051
Cancer target Gene target Drug therapy Evidence level Effect Link (Pubmed)
OV ROS1 Crizotinib 27397505

Drug Therapy

Cancer Type: PAAD
Cancer descriptoin: Pancreatic Adenocarcinoma
Medical Subject Headings (MeSH): D010190
Diseases Database: 9510
Cancer target Gene target Drug therapy Evidence level Effect Link (Pubmed)
PAAD ROS1 Crizotinib 27397505

Drug Therapy

Cancer Type: PRAD
Cancer descriptoin: Prostate Adenocarcinoma
Medical Subject Headings (MeSH): D011471
Diseases Database: 10780
Cancer target Gene target Drug therapy Evidence level Effect Link (Pubmed)
PRAD ROS1 Crizotinib 27397505

Drug Therapy

Cancer Type: STAD
Cancer descriptoin: Stomach Adenocarcinoma
Medical Subject Headings (MeSH): D013274
Diseases Database: 12445
Cancer target Gene target Drug therapy Evidence level Effect Link (Pubmed)
STAD ROS1 Crizotinib 27397505
 Adenocarcinoma (CA ad).
 Melanocytic neoplasm, special type (MELN spec).
22327623
ChiTaRS
2		 t(6;1)(q22;q21.2)
 

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